Economic impact of tibolone compared with continuous-combined hormone replacement therapy in the management of climacteric symptoms in postmenopausal women
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چکیده
Health technology The study assessed a 3-year treatment course of tibolone, a synthetic steroid that has estrogenic, progestogenic and androgenic properties, in the management of postmenopausal women with climacteric symptoms. Tibolone was taken daily at a dose of 2.5 mg and was taken orally. The treatment was compared with continuous combined hormone replacement therapy, which comprised conjugated equine estrogens (CEE) and medroxyprogesterone acetate (MPA) at daily doses of 0.625 mg and 1.5 mg, respectively.
منابع مشابه
Economic impact of Tibolone compared with Continuous-Combined Hormone Replacement Therapy in the management of climacteric symptoms in postmenopausal women.
BACKGROUND Deciding whether to treat postmenopausal women suffering from climacteric symptoms with Continuous Combined Hormone Replacement Therapy (CCHRT) has become increasingly difficult after the release of the Women's Health Initiative results. As a result, development of alternatives to CCHRT is required. Tibolone, which is a synthetic steroid that has estrogenic, progestogenic and androge...
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Tibolone, which is indicated for the relief of climacteric symptoms and the prevention of osteoporosis in postmenopausal women, has a tissue-specific mode of action different to that of conventional hormone replacement therapy (HRT). A large proportion of Asian postmenopausal women experience symptoms that most frequently include musculoskeletal pain, insomnia, forgetfulness, hot flushes and se...
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Different symptoms in Climacteric period, includes hot flash. Hormone replacement therapy (HRT) is common therapy for relief of menopausal symptoms but has possible contraindications and side effects. Recently Piascledine (combination of Avocado oil with Soybean oil) showed effects in reducing hot flash severity. Present study designed to compare the effects of HRT with Piascledine in treatment...
متن کاملComparison of Piascledine (Avocado and Soybean Oil) and Hormone Replacement Therapy in Menopausal-Induced Hot Flashing
Different symptoms in Climacteric period, includes hot flash. Hormone replacement therapy (HRT) is common therapy for relief of menopausal symptoms but has possible contraindications and side effects. Recently Piascledine (combination of Avocado oil with Soybean oil) showed effects in reducing hot flash severity. Present study designed to compare the effects of HRT with Piascledine in treatment...
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OBJECTIVE To compare the effects of tibolone, estriol and conventional hormone replacement therapy (HRT) on mammographic parenchymal density in postmenopausal women. DESIGN AND SETTING This was a non-randomised, prospective, longitudinal, comparative study conducted at two specialist outpatient clinics in Chile. PATIENTS AND PARTICIPANTS 210 non-obese, postmenopausal women aged <65 years wi...
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